Arterial Stiffness and Left Ventricular Diastolic Function in Subjects with Euthyroidism

Objective: Previous literature has suggested that the cardiovascular risk factors associated with subclinical hypothyroidism (SCH) may be found in subjects euthyroidism, but research relating to increased arterial stiffness (AS) and left ventricular (LV) diastolic dysfunction, which have been proven exist patients SCH, is limited euthyroidism. The aim of this study was investigate this. Methods: A total 249 participants euthyroidism were divided into two groups based on their thyroid-stimulating hormone (TSH) levels: Group (TSH level ranging from 0.49 2.5 mIU/L, n = 170) B 4.91 79). Cardiovascular Profiling System through brachial-ankle pulse wave velocity (baPWV) used assess AS, LV function evaluated using Color-Doppler-Echocardiography. Student’s unpaired t-test Pearson’s χ2 test conducted compare clinical parameters. Spearman’s correlation analysis multiple logistic regression analyze association between thyroid function, baPWV, Results: Significant differences existed free triiodothyronine (fT3) values systolic blood pressure (BP) (p < 0.05). When compared A, baPWV higher, increased, E/A ratio lower 0.01). showed fT3 a higher 0.001). directly correlated TSH, fT3, 0.05), BP significantly Thyroperoxidase antibody not significant variable > Conclusions: An Further needed confirm these conclusions.